Today in Bioinformatics we talked about how sequence alignment works for two sequences.

It uses dynamic programming to guarantee that subject to the scoring method we use (and which cannot get particularly complex), we can find the alignment or alignments that is (are) of the best possible total score.

NEXT WEEK – that is, on the 15th of September, I will carry on and talk about multiple sequence alignment.

So this is an additional session. It was generally agreed that this would be a welcome continuation, but you should to course feel free to drop in to learn how multiple sequence alignment is done. There will be plenty of opportunity to ask questions.

If you’ve always wondered whether you should align by hand or by using Muscle, T-Coffee, or some method chosen for you that you just go along with, that would be a good time to ask!

If you’d like to know about BLAST, this would also be a good time.

Cheers for now!

Mike

Michael Charleston
Associate Professor in Bioinformatics
School of Physical Sciences
University of Tasmania
AUSTRALIA
phone: +61 3 6226 2444

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